What is allergy? - Australasian Society of Clinical Immunology and Allergy (ASCIA) (2024)

Frequently Asked Questions

This document has been developed by ASCIA, the peak professional body of clinical immunology/allergy specialists in Australia and New Zealand. ASCIA information is based on published literature and expert review, is not influenced by commercial organisations and is not intended to replace medical advice. For patient or carer support contact Allergy & Anaphylaxis Australia or Allergy New Zealand.

Allergies are increasing in Australia and New Zealand and affect around one in five people. There are many causes of allergy, and symptoms vary from mild to severe. Allergy can also be associated with asthma.

ASCIA PC What is Allergy FAQ 2024122.02 KB

Q 1: What is allergy?

Allergy occurs when a person's immune system reacts to substances in the environment that are harmless to most people. These substances are known as allergens and are found in dust mites, pets, pollen, insects, ticks, moulds, foods, and drugs (medications).

Atopy is the genetic tendency to develop allergic diseases. When atopic people are exposed to allergens, they can develop an immune reaction that leads to allergic inflammation (redness and swelling). This can cause symptoms in the:

  • Nose and/or eyes, resulting in allergic rhinitis (hay fever) and/or conjunctivitis.
  • Skin resulting in eczema, or hives (urticaria).
  • Lungs resulting in asthma.

Q 2: What happens when you have an allergic reaction?

When a person who is allergic to a particular allergen comes into contact with it, an allergic reaction occurs:

  • When the allergen (such as pollen) enters the body, it triggers an antibody response.
  • The antibodies attach themselves to mast cells, which respond by releasing histamine.
  • When the release of histamine is due to an allergen, the resulting inflammation is irritating and uncomfortable.

Similar reactions can occur to some chemicals and food additives. However, if they do not involve the immune system, they are known as adverse reactions, not allergy.

Q 3: Which areas of the body may be affected?

People experience different symptoms, depending on the allergen and where it enters the body. Allergic reactions can involve many parts of the body at the same time.

Nose, eyes, sinuses and throat

When allergens are breathed in, the release of histamine causes the lining of the nose to produce more mucus and become swollen and inflamed. It causes the nose to run and itch, and sneezing may occur. Eyes may start to water, and people may get a sore throat.

Lungs and chest

Asthma can be triggered during an allergic reaction. When an allergen is breathed in, the airways become swollen which makes breathing difficult.

Stomach and bowel

Foods that commonly cause allergy include peanuts, seafood, dairy products, and eggs. Cow's milk allergy in infants (babies) may occur and can cause eczema, asthma, colic, and stomach upset.

Some people cannot digest lactose (milk sugar) which can cause stomach upsets. This is known as lactose intolerance and should not be confused with allergy.

Skin

Skin problems that can triggered by allergy include atopic dermatitis (eczema) and urticaria (hives).

Q 4: How is a severe allergic reaction (anaphylaxis) treated?

Most allergic reactions are mild to moderate, and do not cause major problems. However, a small number of people may experience a severe allergic reaction called anaphylaxis, which requires immediate treatment with adrenaline (epinephrine) which is a life-saving medication. Allergens which may cause anaphylaxis include foods, insects, and drugs. People with a severe allergy should have an ASCIA Action Plan for Anaphylaxis.

Q 5: What effective prevention and treatment options are available?

Allergen avoidance or minimisation relies on identifying the cause of the allergy and taking steps to reduce exposure to the allergen. For example, reducing dust mite in the home may help reduce symptoms in people who are allergic to mites.

Treatments for allergies include:

  • Antihistamine tablets, syrups, intranasal sprays, and eye drops (non-sedating) help to reduce symptoms (sneezing, itchy and irritated eyes), however, are not as effective for reducing nasal symptoms such as a blocked or runny nose. Antihistamine eye drops can be helpful in controlling watery eyes due to allergies. One benefit of antihistamines is that they can be used to treat symptoms when they are present and do not need to be taken when symptoms are not present.
  • Intranasal corticosteroid sprays (INCS) are effective for treatment of moderate to severe allergic rhinitis when used regularly. How INCS are used is also very important so make sure to read the label and ask your pharmacist or doctor for advice.
  • Intranasal corticosteroid spray (INCS) containing antihistamine are available and offer the combined advantages of both medications.
  • Medicated eye drops can be helpful in some cases, ask your pharmacist or doctor for advice.
  • Adrenaline is used for the immediate treatment of anaphylaxis. Adrenaline is usually given using an adrenaline injector that can be given without medical training.
  • Saline (salt water) treatments such as nasal sprays or rinses are safe and effective, helping to clear allergens from the nose and relieve symptoms.
  • Allergen immunotherapy (also known as desensitisation) is a long-term treatment which changes the immune system's response to allergens. It involves the administration of regular, gradually increasing amounts of allergen extracts, by injections or by sublingual tablets, sprays or drops.

If you have an allergy, see your pharmacist or doctor. You may be referred to a clinical immunology/allergy specialist for further assessment and advice.

© ASCIA 2024

Content updated March 2024

For more information go to www.allergy.org.au/patients/information

Tosupportallergyand immunology research go towww.allergyimmunology.org.au/donate

What is allergy? - Australasian Society of Clinical Immunology and Allergy (ASCIA) (2024)

FAQs

What is allergy? - Australasian Society of Clinical Immunology and Allergy (ASCIA)? ›

ASCIA is the peak professional body of clinical immunology and allergy in Australia and New Zealand. ASCIA promotes and advances the study and knowledge of allergy and other immune diseases.

What does ASCIA do? ›

ASCIA's purpose is to advance the science and practice of allergy and clinical immunology. This is achieved by promoting the highest standard of medical practice, training, education and research, to improve the quality of life and health of people with immune system disorders.

What is allergy and clinical immunology? ›

Allergy and immunology is the area of medicine dedicated to the study, diagnosis, and treatment of immune system conditions, including allergic disease and related symptoms and reactions — issues that affect many millions of Americans.

What are the symptoms of ASCIA anaphylaxis? ›

Watch for ANY ONE of the following signs:

Difficult or noisy breathing. Swelling of tongue. Swelling or tightness in throat. Wheeze or persistent cough.

What is the purpose of orange ASCIA first aid plans? ›

The ASCIA First Aid Plan for Anaphylaxis (ORANGE) has been developed for use as a poster, or as an instruction guide to include with an adrenaline injector for general use. Adrenaline injectors for general use can be purchased without a prescription at full price from pharmacies.

What are the two types of ASCIA action plans? ›

There are two types of ASCIA Action Plans for Anaphylaxis (General and Personal): The General version (orange) does not contain any personal information and can be used as a poster.

What are allergy immunology symptoms? ›

Other symptoms may include:
  • Itching and hives over most of the body.
  • Feeling warm.
  • Swelling of the throat and tongue or tightness in throat.
  • Difficulty breathing or shortness of breath.
  • Dizziness.
  • Headache.
  • Pain or cramps.
  • Nausea, vomiting, or diarrhea.

Is allergy and immunology the same as rheumatology? ›

Immunologists and rheumatologists may treat patients of all ages. More specifically, immunologists commonly treat patients with immunologic conditions and allergies. Rheumatologists, however, typically treat patients with autoimmune diseases and musculoskeletal conditions related to bones, joints and muscles.

What does an immunologist test for? ›

The immunologist will perform a series of tests to identify the allergen or substance that's causing your reaction. Each test contains tiny amounts of possible allergens that may trigger an immune response. The testing includes: Blood testing to detect and measure possible allergens in your blood.

What is the difference between an allergy intolerance and anaphylaxis? ›

However, food intolerance does not involve the immune system and does not cause severe allergic reactions (known as anaphylaxis). Food intolerance also does not show on allergy testing, and the Australiasian Society of Clinical Immunology and Allergy (ASCIA) advises against non evidence-based allergy tests .

What 3 things are likely to be seen in an anaphylactic reaction? ›

Skin reactions, including hives and itching and flushed or pale skin. Low blood pressure (hypotension) Constriction of the airways and a swollen tongue or throat, which can cause wheezing and trouble breathing. A weak and rapid pulse.

What is the best antihistamine for anaphylaxis? ›

Diphenhydramine has a long history of efficacy and relative safety. It has an FDA indication for anaphylaxis. IV administration provides faster onset of action.

Can food intolerances be life threatening? ›

Unlike Immunoglobulin E (IgE) antibody mediated food allergy, food intolerances (except for sulphite and benzoate reactions) do not cause anaphylaxis (severe allergic reactions), that can be life threatening.

Can antihistamines prevent anaphylaxis? ›

Although histamine is involved in anaphylaxis, treatment with antihistamines does not relieve or prevent all of the pathophysiological symptoms of anaphylaxis, including the more serious complications such as airway obstruction, hypotension, and shock.

How long does it take for anaphylaxis to start? ›

It mostly occurs within 20 minutes to 2 hours after exposure to the allergen. Signs and symptoms may be mild at first, but can get worse very quickly. A small number of people suddenly develop signs and symptoms of a severe allergic reaction (anaphylaxis) without any signs of a mild to moderate allergic reaction.

What is the main purpose of the allergy regulations? ›

To protect those with food allergies and other food hypersensitivities, the FDA enforces regulations requiring companies to list ingredients on packaged foods and beverages. For certain foods or substances that cause allergies or other hypersensitivity reactions, there are more specific labeling requirements.

How does adrenaline reduce swelling? ›

Heart — it causes the heart to pump faster and harder. This raises your blood pressure and circulates blood more quickly throughout the body. Lungs and airways — your breathing becomes deeper and faster. It dilates the airways and may reduce swelling.

How does histamine help anaphylaxis? ›

Many of these mediators are believed responsible for the pathophysiology of anaphylaxis. Histamine stimulates vasodilation, and increases vascular permeability, heart rate, cardiac contraction, and glandular secretion.

What is the purpose of allergic responses? ›

The function of allergy: immunological defense against toxins.

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