Allergies and asthma: Double trouble (2024)

Allergies and asthma: They often occur together

Allergies and asthma: A Mayo Clinic specialist explains the connection, and what you can do to prevent attacks and manage symptoms.

By Mayo Clinic Staff

Allergies and asthma: Double trouble (1) James T C Li, M.D., Ph.D.

You may wonder what allergies and asthma have in common besides making you miserable. A lot, as it turns out. Allergies and asthma often occur together.

The same substances that trigger your hay fever (allergic rhinitis) symptoms, such as pollen, dust mites and pet dander, may also cause asthma signs and symptoms. In some people, skin or food allergies can cause asthma symptoms. This is called allergic asthma or allergy-induced asthma.

James T C Li, M.D., Ph.D., a Mayo Clinic allergy specialist, answers questions about the link between allergies and asthma.

How does an allergic reaction cause asthma symptoms?

An allergic response occurs when immune system proteins (antibodies) mistakenly identify a harmless substance, such as tree pollen, as an invader. In an attempt to protect your body from the substance, antibodies bind to the allergen.

The chemicals released by your immune system lead to allergy signs and symptoms, such as nasal congestion, runny nose, itchy eyes or skin reactions. For some people, this same reaction also affects the lungs and airways, leading to asthma symptoms.

Are allergies and asthma treated differently?

Most treatments are designed to treat either asthma or allergic rhinitis. But a few treatments help with both conditions. Some examples:

  • Leukotriene modifier. This type of medication can ease both allergic rhinitis and asthma symptoms. Called a leukotriene modifier, this daily pill helps control immune system chemicals released during an allergic reaction. Montelukast (Singulair) is the leukotriene modifier that can treat both asthma and allergic rhinitis.
  • Allergy shots (immunotherapy). Allergy shots can help treat asthma by gradually reducing your immune-system response to certain allergy triggers. Immunotherapy involves getting regular injections of a tiny amount of the allergens that trigger your symptoms.

    Your immune system builds up a tolerance to the allergens over time, and your allergic reactions diminish. In turn, asthma symptoms decrease as well. This treatment generally requires regular injections over a period of time.

  • Anti-immunoglobulin E (IgE) therapy. When you have an allergy, your immune system mistakenly identifies a specific substance as something harmful and releases antibodies, known as IgE, against the culprit allergen.

    The next time you encounter that allergen, the IgE antibodies sense it and signal your immune system to release a chemical called histamine, as well as other chemicals, into your bloodstream. The medication omalizumab (Xolair) interferes with IgE in the body and helps prevent the allergic reaction that triggers asthma symptoms. This treatment is used for more severe allergic asthma, but it might also help allergic rhinitis.

You may need other medications to treat allergies or asthma, especially if your symptoms become severe at times. However, recognizing and avoiding the substances that trigger your symptoms is an important step you can take.

Who's at risk of allergic asthma?

A family history of allergies is a major risk factor for allergic asthma. Having hay fever or other allergies yourself also increases your risk of getting asthma.

Is all asthma caused by allergies?

Though allergic asthma is very common, there are other types of asthma with different kinds of triggers. For some people, asthma can be triggered by exercise, infections, cold air, gastroesophageal reflux disease or stress. Many people have more than one kind of asthma trigger.

Take charge: Get symptoms under control

Know the things that trigger your allergy and asthma symptoms and learn how to limit your exposure to them. Work with your doctor to find the best treatment to manage your symptoms, and check in with your doctor on a regular basis.

Because allergy and asthma symptoms can change over time, you may need to adjust your treatment accordingly. Learn the signs that your asthma may be flaring up — and know what to do when it does.

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May 14, 2021

  1. What does asthma have to do with your allergies? Probably a lot. American College of Allergy, Asthma and Immunology. https://acaai.org/news/what-does-asthma-have-do-your-allergies-probably-lot. Accessed Jan. 27, 2021.
  2. Burks AW, et al. Middleton's Allergy: Principles and Practice. 9th ed. Elsevier; 2020. https://www.clinicalkey.com. Accessed Jan. 27, 2021.
  3. Asthma 101. American College of Allergy, Asthma and Immunology. https://acaai.org/asthma/asthma-101. Accessed Jan. 27, 2021.
  4. Wenzel S. Treatment of severe asthma in adolescents and adults. https://www.uptodate.com/contents/search. Accessed Jan. 27, 2021.
  5. 2020 Focused updates to the asthma management guidelines: A report from the National Asthma Education and Prevention Program Coordinating Committee Expert Panel Working Group. Journal of Allergy and Clinical Immunology. 2020; doi:10.1016/j.jaci.2020.10.003.
  6. Zuberi FF, et al. Role of montelukast in asthma and allergic rhinitis patients. Asthma symptoms. Pakistan Journal of Medical Sciences. 2020; doi:10.12669/pjms.36.7.2657.
  7. Li JTC (expert opinion). Mayo Clinic. Feb. 8, 2021.

See more In-depth

See also

  1. Albuterol side effects
  2. Allergy shots
  3. Aspirin allergy
  4. Asthma
  5. Asthma and acid reflux
  6. Asthma attack
  7. Asthma diet
  8. Asthma inhalers: Which one's right for you?
  9. Asthma: Colds and flu
  10. Asthma medications
  11. Asthma: Testing and diagnosis
  12. Asthma treatment: 3 steps
  13. Cervical cerclage
  14. Churg-Strauss syndrome
  15. COVID-19: Who's at higher risk of serious symptoms?
  16. CT scan
  17. Exercise and chronic disease
  18. Exercise-induced asthma
  19. Intermittent fasting
  20. Laser eye surgery
  21. Methacholine challenge test
  22. Nitric oxide test for asthma
  23. Occupational asthma
  24. Ozone air purifiers
  25. Prednisone risks, benefits
  26. Prednisone withdrawal: Why taper down slowly?
  27. Shortness of breath
  28. Spirometry
  29. Symptom Checker
  30. Asthma attack video
  31. Dry powder disk inhaler
  32. Dry powder tube inhaler
  33. Video: How to use a peak flow meter
  34. Single-dose dry powder inhaler
  35. Using a metered dose asthma inhaler and spacer
  36. Vocal cord dysfunction
  37. What is aspirin-exacerbated respiratory disease (AERD)?
  38. Wheezing
  39. X-ray

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